Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 82, Issue 2 , Pages 131-139 , February 2010

Hypertonic environment elicits cyclooxygenase-2-driven prostaglandin E2 generation by colon cancer cells: Role of cytosolic phospholipase A2-α and kinase signaling pathways

  • Luciana B. Gentile

      Affiliations

    • Divisão de Biologia Celular, Coordenação de Pesquisa, Instituto Nacional de Câncer, Rio de Janeiro, RJ 20231-050, Brazil
    • Programa de Pós-Graduação em Ciências Morfológicas, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-902, Brazil
  • ,
  • Bruno Piva

      Affiliations

    • Laboratório de Inflamação, Programa de Imunobiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho 373, Bloco C, room C1-024, Rio de Janeiro, RJ, CEP 21941-902, Brazil
  • ,
  • Bianca C. Capizzani

      Affiliations

    • Laboratório de Inflamação, Programa de Imunobiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho 373, Bloco C, room C1-024, Rio de Janeiro, RJ, CEP 21941-902, Brazil
  • ,
  • Luiz G.B. Furlaneto

      Affiliations

    • Divisão de Biologia Celular, Coordenação de Pesquisa, Instituto Nacional de Câncer, Rio de Janeiro, RJ 20231-050, Brazil
  • ,
  • Luciana S. Moreira

      Affiliations

    • Divisão de Biologia Celular, Coordenação de Pesquisa, Instituto Nacional de Câncer, Rio de Janeiro, RJ 20231-050, Brazil
  • ,
  • Daniel Zamith-Miranda

      Affiliations

    • Laboratório de Inflamação, Programa de Imunobiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho 373, Bloco C, room C1-024, Rio de Janeiro, RJ, CEP 21941-902, Brazil
  • ,
  • Bruno L. Diaz

      Affiliations

    • Laboratório de Inflamação, Programa de Imunobiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho 373, Bloco C, room C1-024, Rio de Janeiro, RJ, CEP 21941-902, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: +552125626509; fax: +552122808193.

Received 5 December 2008 ,Revised 11 November 2009 ,Accepted 12 November 2009.

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 Funded by BZG.

PII: S0952-3278(09)00199-9

doi: 10.1016/j.plefa.2009.11.005

Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 82, Issue 2 , Pages 131-139 , February 2010