Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 82, Issue 2 , Pages 97-103 , February 2010

Prophylactic and therapeutic effects of Mytilus edulis fatty acids on adjuvant-induced arthritis in male Wistar rats

  • Sarah McPhee

      Affiliations

    • Natural Products Research Group, School of Medical Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    • ,
  • Lynn D. Hodges

      Affiliations

    • Natural Products Research Group, School of Medical Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    • ,
  • Paul F.A. Wright

      Affiliations

    • Key Centre for Toxicology, School of Medical Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    • ,
  • Paul M. Wynne

      Affiliations

    • SGE International Pty Ltd., Ringwood, Victoria 3134, Australia
    • ,
  • Nicolette Kalafatis

      Affiliations

    • Natural Products Research Group, School of Medical Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    • ,
  • Theodore A. Macrides

      Affiliations

    • Natural Products Research Group, School of Medical Sciences, RMIT University, Bundoora, Victoria 3083, Australia
    • Corresponding Author InformationCorresponding author. Tel.: +61399257070; fax: +61399257063.

Received 25 February 2009 ,Revised 4 December 2009 ,Accepted 9 December 2009.

References 

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  2. Charlier C, Michaux C. Dual inhibition of cyclooxygenase-2 (COX-2) and 5 lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs. Eur. J. Med. Chem. 2003;38:645–659
  3. Calder PC. PUFA, inflammatory processes and rheumatoid arthritis. Proc. Nutr. Soc. 2008;67:409–418
  4. Claria J, Romano M. Pharmacological intervention of cyclooxygenase-2 and 5-lipoxygenase pathways: impact on inflammation and cancer. Curr. Pharm. Des. 2005;11:3431–3447
  5. Gil A. Polyunsaturated fatty acids and inflammatory diseases. Biomed. Pharmacother. 2002;56:388–396
  6. Stamp LK, James MJ, Cleland LG. Diet and rheumatoid arthritis: a review of the literature. Semin. Arthritis Rheum. 2005;35:77–94
  7. FAO 2004-2008, in: P. Goulletquer (Ed.), FAO Fisheries and Aquaculture Department, Rome, Updated 1 January 2004, [online, Cited 9 December 2008]. 〈http://www.fao.org/fishery/culturedspecies/Mytilus_edulis〉.
  8. Yearsley GK, Last PR, Ward RD. Australian seafood domestic species, FRDC Project 95/122. Hobart, Australia: CSIRO Marine Research; 1998;pp. 335-409
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  10. Murphy KJ, Mooney BD, Mann NJ, Nichols PD, Sinclair AJ, Lipid FA. Sterol composition of New Zealand green-lipped mussel (Perna canaliculus) and Tasmanian blue mussel (Mytilus edulis). Lipids. 2002;37:587–595
  11. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can. J. Biochem. 1959;37:911–917
  12. Christie WW. Lipid Analysis. second ed.. Oxford, UK: Pergamon Press; 1982;p. 82
  13. AOAC, Methyl esters of fatty acids in oils and fats: gas chromatography method, in: Official Methods of the Association of Official Analytical Chemists, Arlington, VA, 1995, Method 96322.
  14. Treschow AP, Hodges LD, Wright PFA, Wynne PM, Kalafatis N, Macrides TA. Novel anti-inflammatory ω-3 PUFAs from the New Zealand green-lipped mussel, Perna canaliculus. Comp. Biochem. Physiol. Part B. 2007;147:645–656
  15. Sheean PD, Hodges LD, Kalafatis N, Wright PFA, Wynne PM, Whitehouse MW, et al. Bioactivity of extracts from gonadal tissue of the edible Australian purple sea urchin Heliocidaris erythrogramma. J. Sci. Food Agric. 2007;87:694–701
  16. Pittiglio DH, Sacher RA. Clinical Hematology and Fundamentals of Hemostasis. Philadelphia: F.A Davis Company; 1987;
  17. McColl SR, Cleland LG, Whitehouse MW, Vernon-Roberts B. Effect of dietary polyunsaturated fatty acid (PUFA) supplementation on adjuvant induced polyarthritis in rats. J. Rheumatol. 1987;14:197–201
  18. Singh M, Hodges LD, Wright PFA, Cheah DMY, Wynne PM, Kalafatis N, et al. The CO2-SFE crude lipid extract and the free fatty acid extract from Perna canaliculus have anti-inflammatory effects on adjuvant-induced arthritis in rats. Comp. Biochem. Physiol. Part B. 2008;149:251–258
  19. T.A. Macrides, N. Kalafatis, Anti-inflammatory preparation, International Patent Application PCT/AU95/00485, 1995.
  20. Whitehouse MW, Macrides TA, Kalafatis N, Betts WH, Haynes DR, Broadbent J. Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel. Inflammopharmacology. 1997;5:237–246
  21. Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 2008;8:349–361

PII: S0952-3278(09)00206-3

doi: 10.1016/j.plefa.2009.12.003

Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 82, Issue 2 , Pages 97-103 , February 2010

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