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Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 82, Issue 4
, Pages 281-285
, April 2010
Alternative transcripts of fatty acid desaturase (FADS) genes
References
- . Fatty acid delta 5 desaturation in rat liver cell nuclei. Mol. Cell Biochem. 1995;142:163–170
- Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids. J. Lipid Res. 1995;36:2471–2477
- . Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog. Lipid. Res. 2006;45:237–249
- . Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Ann. Rev. Nutr. 2004;24:345–376
- . Cloning, expression, and fatty acid regulation of the human delta-5 desaturase. J. Biol. Chem. 1999;274:37335–37339
- . Cloning, expression, and nutritional regulation of the mammalian delta-6 desaturase. J. Biol. Chem. 1999;274:471–477
- . Simultaneous measurement of desaturase activities using stable isotope tracers or a nontracer method. Anal. Biochem. 1998;261:43–50
- Cdna cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family. Genomics. 2000;66:175–183
- Common genetic variants of the fads1 fads2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum. Mol. Genet. 2006;15:1745–1756
- Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (fads1 fads2) gene cluster and the fatty acid composition of erythrocyte membranes. Br. J. Nutr. 2008;1–7
- Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 2008;4:e1000282
- Snps of the fads gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease. Lipids. 2008;43:289–299
- . Genetic variants of the fads1 fads2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation. J. Nutr. 2008;138:2222–2228
- Association of fatty acid desaturase genes with attention-deficit/hyperactivity disorder. Biol. Psychiatry. 2006;60:1053–1061
- . Why genes in pieces?. Nature. 1978;271:501.
- Dscam diversity is essential for neuronal wiring and self-recognition. Nature. 2007;449:223–227
- Dendrite self-avoidance is controlled by dscam. Cell. 2007;129:593–604
- Alternate transcripts expressed in response to diet reflect tissue-specific regulation of abca1. J. Lipid. Res. 2005;46:2061–2071
- An alternate pathway to long-chain polyunsaturates: the fads2 gene product delta8-desaturates 20:2n-6 and 20:3n-3. J. Lipid. Res. 2009;50:1195–1202
- Novel fatty acid desaturase 3 (fads3) transcripts generated by alternative splicing. Gene. 2009;
- Park, W.J., Reardon, H.T., Tyburczy, C., et al. Alternative splicing generates a novel fads2 alternative transcript in baboons. Mol. Biol. Rep. (2009) [Epub ahead of print].
- Identification of the delta-6 desaturase of human sebaceous glands: expression and enzyme activity. J. Invest. Dermatol. 2003;120:707–714
- Molecular cloning and functional characterization of fatty acyl desaturase and elongase cdnas involved in the production of eicosapentaenoic and docosahexaenoic acids from alpha-linolenic acid in atlantic salmon (salmo salar). Mar. Biotechnol. (NY). 2004;6:463–474
- . Identification of an animal omega-3 fatty acid desaturase by heterologous expression in arabidopsis. Proc. Natl. Acad. Sci. USA. 1997;94:1142–1147
- Cloning and characterization of unusual fatty acid desaturases from anemone leveillei: identification of an acyl-coenzyme a c20 delta5-desaturase responsible for the synthesis of sciadonic acid. Plant Physiol. 2007;144:455–467
- . Delta-6 desaturation of alpha-linolenic acid in brain and liver during development and aging in the mouse. Neurosci. Lett. 1992;141:65–68
- Biosynthesis of docosahexaenoic acid in human cells: evidence that two different delta 6-desaturase activities may exist. Biochim. Biophys. Acta. 1996;1301:263–272
- . Gene cloning and functional analysis of a second delta 6-fatty acid desaturase from an arachidonic acid-producing mortierella fungus. Biosci. Biotechnol. Biochem. 2003;67:704–711
- . Analysis of the putative role of 24-carbon polyunsaturated fatty acids in the biosynthesis of docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids. FEBS Lett. 1998;431:1–6
- Straight-chain acyl-coa oxidase knockout mouse accumulates extremely long chain fatty acids from alpha-linolenic acid: evidence for runaway carousel-type enzyme kinetics in peroxisomal beta-oxidation diseases. Mol. Genet. Metab. 2002;75:108–119
- Long chain polyunsaturated fatty acid formation in neonates: effect of gestational age and intrauterine growth. Pediatr. Res. 2000;47:127–135
- . Are eskimos obligate carnivores?. Lancet. 1981;1:1100.
PII: S0952-3278(10)00055-4
doi: 10.1016/j.plefa.2010.02.011
© 2010 Elsevier Ltd. All rights reserved.
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Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 82, Issue 4
, Pages 281-285
, April 2010
