« Previous
Next »
Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 83, Issue 3
, Pages 131-136
, September 2010
Polyunsaturated fatty acids deficits are associated with psychotic state and negative symptoms in patients with schizophrenia
References
- . Effects of different dietary levels of essential fatty acids on the fatty acid composition of ethanolamine phosphoglycerides in myelin and synaptosoma plasma membranes. J. Neurochem. 1975;25:101–107
- . Schizophrenia as a prostaglandin deficiency disease. Lancet. 1977;1:936–937
- . Red blood cell membrane dynamics in schizophrenia. II. Fatty acid composition. Schizophr. Res. 1994;13:217–226
- . A red cell membrane abnormality in a subgroup of schizophrenic patients: evidence for two diseases. Schizophr. Res. 1994;12:53–61
- . Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. Prostaglandins Leukot. Essent. Fatty Acids. 1996;55:71–75
- . Reduced erythrocyte membrane essential fatty acids and increased lipid peroxides in schizophrenia at the never-medicated first-episode of psychosis and after years of treatment with antipsychotics. Schizophr. Res. 2002;58:1–10
- . Significantly reduced docosahexaenoic and docosapentaenoic acid concentrations in erythrocyte membranes from schizophrenic patients compared with a carefully matched control group. Biol. Psychiatry. 2001;49:510–522
- . Red blood cell membrane essential fatty acid metabolism in early psychotic patients following antipsychotic drug treatment. Prostaglandins Leukot. Essent. Fatty Acids. 2003;69:393–399
- . Essential polyunsaturated fatty acid and lipid peroxide levels in never-medicated and medicated schizophrenia patients. Biol. Psychiatry. 2003;53:56–64
- . Reduced red blood cell membrane essential polyunsaturated fatty acids in first episode schizophrenia at neuroleptic-naive baseline. Schizophr. Bull. 2004;30:901–911
- . Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 2000;(Text Revision)
- . Techniques in Diagnostic Human Biochemical Genetics. New York: Wiley; 1991;p. 177
- . Essential fatty acids, lipid membrane abnormalities, and the diagnosis and treatment of schizophrenia. Biol. Psychiatry. 2000;47:8–21
- . Essential fatty acids are mediators of brain biochemistry and cognitive functions. J. Neurosci. Res. 1999;56:565–570
- . Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature. 1989;342:918–920
- . Inhibition of astroglial glutamate transport by polyunsaturated fatty acids: evidence for a signalling role of docosahexaenoic acid. Neurochem. Int. 2009;54:535–543
- . Modulation of phosphoinositide–protein kinase C signal transduction by omega-3 fatty acids: implications for the pathophysiology and treatment of recurrent neuropsychiatric illness. Prostaglandins Leukot. Essent. Fatty Acids. 2006;75:237–257
- . Smoking, gender, and dietary influences on erythrocyte essential fatty acid composition among patients with schizophrenia or schizoaffective disorder. Biol. Psychiatry. 2003;53:431–441
- . Nutrition and schizophrenia: beyond omega-3 fatty acids. Prostaglandins Leukot. Essent. Fatty Acids. 2004;70:417–422
- . Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1–FADS2) gene cluster and the fatty acid composition of erythrocyte membranes. Br. J. Nutr. 2009;101:20–26
- . Increased phospholipid breakdown in schizophrenia. Evidence for the involvement of a calcium-independent phospholipase A2. Arch. Gen. Psychiatry. 1997;54:487–494
- . Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients. Psychiatry Res. 2003;121:109–122
- . Environmental factors and membrane polyunsaturated fatty acids in schizophrenia. Prostaglandins Leukot. Essent. Fatty Acids. 2003;69:385–391
- . The impact of age, body mass index, and fish intake on the EPA and DHA content of human erythrocytes. Lipids. 2005;40:343–347
- . Essential polyunsaturated fatty acids and social cognition in schizophrenia. Psychiatry Res. 2008;157:87–93
- . Omega-3 fatty acids: a comprehensive review of their role in health and disease. Postgrad. Med. J. 2009;85:84–90
- . A comparison of ten-year cardiac risk estimates in schizophrenia patients from the CATIE study and matched controls. Schizophr. Res. 2005;80:45–53
- . The metabolic syndrome, omega-3 fatty acids and inflammatory processes in relation to schizophrenia. Prostaglandins Leukot. Essent. Fatty Acids. 2006;75:323–327
- . Fatty acids and schizophrenia. Lipids. 1996;31:163–165
- . Do we still believe in the dopamine hypothesis? New data bring new evidence. Int. J. Neuropsychopharmacol. 2004;7:1–5
- . The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids. Am. J. Clin. Nutr. 2002;75:662–667
- . Abnormalities in the fatty acid composition of the postmortem orbitofrontal cortex of schizophrenic patients: gender differences and partial normalization with antipsychotic medications. Schizophr. Res. 2007;91:37–50
- . Omega-3 and omega-6 fatty acid concentrations in red blood cell membranes relate to schizotypal traits in healthy adults. Prostaglandins Leukot. Essent. Fatty Acids. 2003;69:461–466
- . Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. Pharmacogenomics J. 2005;5:298–304
- . Chronic risperidone treatment preferentially increases rat erythrocyte and prefrontal cortex omega-3 fatty acid composition: evidence for augmented biosynthesis. Schizophr. Res. 2009;107:150–157
- . Common effect of antipsychotics on the biosynthesis and regulation of fatty acids and cholesterol supports a key role of lipid homeostasis in schizophrenia. Schizophr. Res. 2009;108:134–142
- . Partial adherence to antipsychotic medication impacts the course of illness in patients with schizophrenia: a review. Prim. Care Companion J. Clin. Psychiatry. 2009;11:147–154
PII: S0952-3278(10)00116-X
doi: 10.1016/j.plefa.2010.07.001
© 2010 Elsevier Ltd. All rights reserved.
« Previous
Next »
Prostaglandins, Leukotrienes and Essential Fatty Acids
Volume 83, Issue 3
, Pages 131-136
, September 2010
