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Abstract
The formation of prostaglandins by vesicular gland cyclooxygenase can be regulated
by O2 concentrations below 30 μ![Math Eq]()
(20 mm Hg) with an apparent Km value of about 5 μM. This result suggests that most mammalian tissues might be expected
normally to have sufficient O2 for some synthesis, and that only occasionally, would the level of oxygen available
within some tissues become marginally inadequate to sustain a high rate of prostaglandin
biosynthesis.
(20 mm Hg) with an apparent Km value of about 5 μM. This result suggests that most mammalian tissues might be expected
normally to have sufficient O2 for some synthesis, and that only occasionally, would the level of oxygen available
within some tissues become marginally inadequate to sustain a high rate of prostaglandin
biosynthesis.To read this article in full you will need to make a payment
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Article info
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Copyright
© 1978 Published by Elsevier Inc.
