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Abstract
The biochemical essential fatty acid (EFA) status of neonates born after normal and
hypertensive pregnancies (PIH) and that of their mothers was assessed by measuring
the fatty acid composition of phospholipids (PL), triglycerides (TG) and cholesterol
esters (CE) of umbilical cord serum and maternal serum, respectively.
Relative contents of linoleic acid of serum PL and CE were significantly lower in
mothers with PIH compared to normal pregnancies. Most other (n-6) polyenes in PL tended
to be higher under hypertensive conditions. Total maternal (n-3) polyenes of serum
PL were significantly higher in PIH, mainly due to clupanodonic acid, 22:5 (n-3),
and cervonic acid, 22:6 (n-3). Total maternal (n-7) and (n-9) fatty acids were also
significantly higher in PIH (PL and CE).
The results indicate that PIH is associated with a relative increased unsaturation
of maternal serum PL, which might facilitate the placental transfer of long-chain,
polyunsaturated fatty acids. As a result, the neonatal EFA status after PIH only slightly
differs from normal.
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Article info
Publication history
Accepted:
July 3,
1991
Received:
December 12,
1990
Identification
Copyright
© 1991 Published by Elsevier Inc.
