Short note| Volume 44, ISSUE 4, P257-258, December 1991

Linoleic acid — Dependent slowing of erythrocyte sedimentation in multiple sclerosis

  • M. Mayer
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    Department of Neurology, Medical Faculty of the Palacký University, I. P. Pavlova 13, 775 00, Olomouc, Czechoslovakia
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      The influence of linoleic acid upon the sedimentation of washed erythrocytes from multiple sclerosis patients and controls was investigated in the present study. Linoleic acid, especially in the concentration of 250 μM and 500 μM, caused slowing of erythrocyte sedimentation and this effect was significantly greater in multiple sclerosis than in controls. These findings with all probability reflect an unsaturated fatty acid-dependent membrane alteration in multiple sclerosis and are analogous to results obtained earlier by several authors by using cytopherometric measurements.
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