Abstract
Recently, in a supplementation study over six months, it has been demonstrated that
re-esterified omega-3 fatty acid triacylglycerols (n3-FA-rTAGs) led to a higher increase
in omega-3-index compared to identical doses of n3-FA ethyl-esters (n3-FA-EEs), suggesting
a better long-term bioavailability. The aim of this study was to examine whether differences
occur between the two forms in affecting fasting serum lipid levels. 150 dyslipidemic
statin-treated participants were randomized to corn oil as a placebo or fish oil either
as rTAG or EE in identical doses (1.01 g EPA+0.67 g DHA). No changes in total cholesterol, HDL or LDL levels were observed. In the rTAG-group,
but not in the EE-group, fasting serum TAG levels were significantly reduced from
baseline after three and six months. There was no significant difference between the
two n3-FA-groups. However, serum TAG levels were significantly lowered after six months
in the rTAG-group compared to the placebo-group in contrast to the EE-group.
Keywords
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Article info
Publication history
Published online: August 24, 2011
Accepted:
July 25,
2011
Received in revised form:
July 22,
2011
Received:
April 13,
2011
Identification
Copyright
© 2011 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
