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Letter| Volume 85, ISSUE 6, P403-404, December 2011

Letter to the Editor

Published:October 24, 2011DOI:https://doi.org/10.1016/j.plefa.2011.09.002
      Blasbalg et al. [

      L. Blasbalg, J.R. Hibbeln, C.E. Ramsden, et al., Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. American Journal of Clinical Nutrition. doi:10.3945/ajcn.110.006643.

      ] have brought to our attention the large increase in LA intakes in the US, which is also reflected in Australian dietary patterns [
      • Meyer B.J.
      • Mann N.J.
      • Lewis J.L.
      • Milligan G.C.
      • Sinclair A.J.
      • Howe P.R.
      Dietary intakes and food sources of omega-6 and omega-3 polyunsaturated fatty acids.
      ]. They have pointed out that despite the fact that these high intakes of LA have occurred against a background of relatively constant n-3 LCPUFA intakes, nevertheless the n-3 LCPUFA status of people has declined. They have also presented data to suggest that the main driver for the decrease in n-3 LCPUFA status in US citizens is likely to be high dietary LA rather than any decline in n-3 LCPUFA intake. This proposal seems logical given the many reports of inhibition of incorporation of n-3 LCPUFA by LA [
      • McMurchie E.J.
      • Rinaldi J.A.
      • Burnard S.L.
      • Patten G.S.
      • Neumann M.A.
      • Mcintosh G.H.
      • Abbey M.A.
      • Gibson R.A.
      Incorporation and effects of dietary eicosapentaenoate (20:5n-3) on plasma and erythrocyte lipids of the marmoset following dietary supplementation with differing levels of linoleic acid.
      ,
      • Cleland L.G.
      • James M.J.
      • Neumann M.A.
      • D'angelo M.D.
      • Gibson R.A.
      Linoleate inhibits EPA incorporation from dietary fish oil supplements in human subjects.
      ].
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      References

      1. L. Blasbalg, J.R. Hibbeln, C.E. Ramsden, et al., Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. American Journal of Clinical Nutrition. doi:10.3945/ajcn.110.006643.

        • Meyer B.J.
        • Mann N.J.
        • Lewis J.L.
        • Milligan G.C.
        • Sinclair A.J.
        • Howe P.R.
        Dietary intakes and food sources of omega-6 and omega-3 polyunsaturated fatty acids.
        Lipids. 2003; 38: 391-398
        • McMurchie E.J.
        • Rinaldi J.A.
        • Burnard S.L.
        • Patten G.S.
        • Neumann M.A.
        • Mcintosh G.H.
        • Abbey M.A.
        • Gibson R.A.
        Incorporation and effects of dietary eicosapentaenoate (20:5n-3) on plasma and erythrocyte lipids of the marmoset following dietary supplementation with differing levels of linoleic acid.
        Biochimica et Biophysica Acta. 1990; 1045 (IF=4.224 (16)): 164-173
        • Cleland L.G.
        • James M.J.
        • Neumann M.A.
        • D'angelo M.D.
        • Gibson R.A.
        Linoleate inhibits EPA incorporation from dietary fish oil supplements in human subjects.
        American Journal of Clinical Nutrition. 1992; 55 (IF=5.853 (60)): 395-399
        • Hansen A.E.
        • Haggard M.E.
        • Boelshe A.N.
        • Adam D.J.
        • Wiese H.F.
        Essential fatty acids in infant nutrition. III. Clinical manifestations of linoleic acid deficiency.
        Journal of Nutrition. 1958; 66: 565-676
        • Cuthbertson W.F.J.
        Essential fatty acid requirement in infancy.
        American Journal of Clinical Nutrition. 1976; 29: 559-568
        • Holman R.T.
        The ratio of trienoic: tetraenoic acids in tissue lipids as a measure of essential fatty acid deficiency.
        Journal of Nutrition. 1960; 70: 405-410
        • Makrides M.
        • Neumann M.
        • Simmer K.
        • Pater J.
        • Gibson R.
        Are long-chain polyunsaturated fatty acids essential nutrients in infancy?.
        Lancet. 1995; 345: 1463-1468
        • Makrides M.
        • Neumann M.A.
        • Jeffrey B.
        • Lien E.L.
        • Gibson R.A.A.
        randomized trial of different ratios of linoleic to alpha-linolenic acid in the diet of term infants: effects on visual function and growth.
        American Journal of Clinical Nutrition. 2000; 71: 120-139
      2. K. Simmer, S.M. Schulzke, S. Patole, Long chain polyunsaturated fatty acid supplementation in preterm infants. Cochrane Database Syst. Rev. 2008 Jan 23;(1):CD000375. Review. Update in: Cochrane Database Syst. Rev. 011;2:CD000375.

        • Gibson R.A.
        • Muhlhausler B.
        • Makrides M.
        Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life.
        Maternal and Child Nutrition. 2011; 7: 17-26
        • Sanders T.A.
        • Naismith D.J.
        A comparison of the influence of breast-feeding and bottle-feeding on the fatty acid composition of the erythrocytes.
        British Journal of Nutrition. 1979; 41: 619-623
        • Courage M.L.
        • McCloy U.R.
        • Herzberg G.R.
        • et al.
        Visual development and fatty acid composition of erythrocytes in full term infants fed breast milk, commercial formula, or evaporated milk.
        Journal of Developmental and Behavioral Pediatrics. 1998; 19: 9-17
        • Munakata M.
        • Nishikawa M.
        • Togashi N.
        • Nio E.
        • Kobayashi Y.
        • Omura K.
        • Haginoya K.
        • Tanaka S.
        • Abe T.
        • Hishinuma T.
        • Chida N.
        • Tsuchiya S.
        • Onuma A.
        The nutrient formula containing eicosapentaenoic acid and docosahexaenoic acid benefits the fatty acid status of patients receiving long-term enteral nutrition.
        Tohoku Journal of Experimental Medicine. 2009; 217: 23-38
        • Guesnet P.
        • Lallemand S.-M.
        • Alessandri J.-M.
        • Join M.
        • Cunnane S.-C.
        α-Linolenate reduces the dietary requirement for linoleate in the growing rat.
        Prostaglandins Leukotrients Essent Fatty Acids. 2011; 85: 353-360