Highlights
- •The ISSFAL Official Statement Number 6 has been approved for publication by the ISSFAL Board of Directors on 9 October 2019.
- •There are many factors associated with n-3 LCPUFA levels and these have been described in a systematic literature review [1].
- •This statement highlights the importance of measuring blood omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) levels in research.
Abstract
A statement on measuring blood omega-3 long chain polyunsaturated fatty acid levels
was developed and edited based on input from ISSFAL members and accepted by vote of
the ISSFAL Board of Directors.
Summary of Statement: Omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) levels
at baseline and post-intervention should be assessed and reported in future research
to evaluate the efficacy of n-3 LCPUFA supplementation: b
ecause; 1. there are numerous factors that affect n-3 LCPUFA levels in humans as described
in the systematic literature review [
[1]
]; 2. assessing intake of n-3 LCPUFA from the diet and/or supplements is not sufficient
to accurately determine n-3 LCPUFA levels in humans; 3. some studies do not provide
sufficient doses of n-3 LCPUFA to produce a significant impact on bloodstream/organ
content and there is substantial variability in the uptake of n-3 LPCUFA into tissues
between individuals. In secondary analyses, clinical trials should consider the influence
of fatty acid status (baseline, endpoint and change from baseline to endpoint) on
the outcome variables.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: November 06, 2019
Accepted:
November 5,
2019
Received:
October 14,
2019
Identification
Copyright
© 2019 Elsevier Ltd. All rights reserved.
